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Applying exercise capacity and physical activity as single vs. composite endpoints for trials of cardiac rehabilitation interventions: Rationale, use-case, and a blueprint method for sample size calculation.
Carrozzo AE, Cornelissen V, Bathke AC, Claes J, Niebauer J, Zimmermann G, Treff G, Kulnik ST. Carrozzo AE, et al. Arch Phys Med Rehabil. 2024 Apr 13:S0003-9993(24)00941-9. doi: 10.1016/j.apmr.2024.04.004. Online ahead of print. Arch Phys Med Rehabil. 2024. PMID: 38621456