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Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis.
Cell. 2024 Apr 17:S0092-8674(24)00397-0. doi: 10.1016/j.cell.2024.04.002. Online ahead of print.
Cell. 2024.
PMID: 38653238
BCAA-nitrogen flux in brown fat controls metabolic health independent of thermogenesis.
Verkerke ARP, Wang D, Yoshida N, Taxin ZH, Shi X, Zheng S, Li Y, Auger C, Oikawa S, Yook JS, Granath-Panelo M, He W, Zhang GF, Matsushita M, Saito M, Gerszten RE, Mills EL, Banks AS, Ishihama Y, White PJ, McGarrah RW, Yoneshiro T, Kajimura S.
Verkerke ARP, et al.
Cell. 2024 Apr 17:S0092-8674(24)00346-5. doi: 10.1016/j.cell.2024.03.030. Online ahead of print.
Cell. 2024.
PMID: 38653240
Free article.
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Integrative spatial analysis reveals a multi-layered organization of glioblastoma.
Greenwald AC, Darnell NG, Hoefflin R, Simkin D, Mount CW, Gonzalez Castro LN, Harnik Y, Dumont S, Hirsch D, Nomura M, Talpir T, Kedmi M, Goliand I, Medici G, Laffy J, Li B, Mangena V, Keren-Shaul H, Weller M, Addadi Y, Neidert MC, Suvà ML, Tirosh I.
Greenwald AC, et al.
Cell. 2024 Apr 16:S0092-8674(24)00320-9. doi: 10.1016/j.cell.2024.03.029. Online ahead of print.
Cell. 2024.
PMID: 38653236
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Gut symbionts alleviate MASH through a secondary bile acid biosynthetic pathway.
Nie Q, Luo X, Wang K, Ding Y, Jia S, Zhao Q, Li M, Zhang J, Zhuo Y, Lin J, Guo C, Zhang Z, Liu H, Zeng G, You J, Sun L, Lu H, Ma M, Jia Y, Zheng MH, Pang Y, Qiao J, Jiang C.
Nie Q, et al.
Cell. 2024 Apr 17:S0092-8674(24)00350-7. doi: 10.1016/j.cell.2024.03.034. Online ahead of print.
Cell. 2024.
PMID: 38653239
Free article.
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DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
Takahashi M, Chong HB, Zhang S, Yang TY, Lazarov MJ, Harry S, Maynard M, Hilbert B, White RD, Murrey HE, Tsou CC, Vordermark K, Assaad J, Gohar M, Dürr BR, Richter M, Patel H, Kryukov G, Brooijmans N, Alghali ASO, Rubio K, Villanueva A, Zhang J, Ge M, Makram F, Griesshaber H, Harrison D, Koglin AS, Ojeda S, Karakyriakou B, Healy A, Popoola G, Rachmin I, Khandelwal N, Neil JR, Tien PC, Chen N, Hosp T, van den Ouweland S, Hara T, Bussema L, Dong R, Shi L, Rasmussen MQ, Domingues AC, Lawless A, Fang J, Yoda S, Nguyen LP, Reeves SM, Wakefield FN, Acker A, Clark SE, Dubash T, Kastanos J, Oh E, Fisher DE, Maheswaran S, Haber DA, Boland GM, Sade-Feldman M, Jenkins RW, Hata AN, Bardeesy NM, Suvà ML, Martin BR, Liau BB, Ott CJ, Rivera MN, Lawrence MS, Bar-Peled L.
Takahashi M, et al.
Cell. 2024 Apr 17:S0092-8674(24)00318-0. doi: 10.1016/j.cell.2024.03.027. Online ahead of print.
Cell. 2024.
PMID: 38653237
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Evasion of NKG2D-mediated cytotoxic immunity by sarbecoviruses.
Hartmann JA, Cardoso MR, Talarico MCR, Kenney DJ, Leone MR, Reese DC, Turcinovic J, O'Connell AK, Gertje HP, Marino C, Ojeda PE, De Paula EV, Orsi FA, Velloso LA, Cafiero TR, Connor JH, Ploss A, Hoelzemer A, Carrington M, Barczak AK, Crossland NA, Douam F, Boucau J, Garcia-Beltran WF.
Hartmann JA, et al.
Cell. 2024 Apr 11:S0092-8674(24)00317-9. doi: 10.1016/j.cell.2024.03.026. Online ahead of print.
Cell. 2024.
PMID: 38653235
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