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The secreted micropeptide C4orf48 enhances renal fibrosis via an RNA-binding mechanism.
Yang J, Zhuang H, Li J, Nunez-Nescolarde AB, Luo N, Chen H, Li A, Qu X, Wang Q, Fan J, Bai X, Ye Z, Gu B, Meng Y, Zhang X, Wu D, Sia Y, Jiang X, Chen W, Combes AN, Nikolic-Paterson DJ, Yu X. Yang J, et al. J Clin Invest. 2024 Apr 16:e178392. doi: 10.1172/JCI178392. Online ahead of print. J Clin Invest. 2024. PMID: 38625739 Free article.
The estrogen signaling pathway reprograms prostate cancer cell metabolism and supports proliferation and disease progression.
Lafront C, Germain L, Campolina-Silva GH, Weidmann C, Berthiaume L, Hovington H, Brisson H, Jobin C, Frégeau-Proulx L, Cotau R, Gonthier K, Lacouture A, Caron P, Ménard C, Atallah C, Riopel J, Latulippe É, Bergeron A, Toren P, Guillemette C, Pelletier M, Fradet Y, Belleannée C, Pouliot F, Lacombe L, Lévesque É, Audet-Walsh É. Lafront C, et al. J Clin Invest. 2024 Apr 16:e170809. doi: 10.1172/JCI170809. Online ahead of print. J Clin Invest. 2024. PMID: 38625747 Free article.