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Proteomic markers with prognostic impact on outcome of chronic lymphocytic leukemia patients under chemo-immunotherapy: results from the HOVON 109 study.
Saberi Hosnijeh F, van der Straten L, Kater AP, van Oers MHJ, Posthuma WFM, Chamuleau MED, Bellido M, Doorduijn JK, van Gelder M, Hoogendoorn M, de Boer F, Te Raa GD, Kerst JM, Marijt EWA, Raymakers RAP, Koene HR, Schaafsma MR, Dobber JA, Tonino SH, Kersting SS, Langerak AW, Levin MD. Saberi Hosnijeh F, et al. Among authors: langerak aw. Exp Hematol. 2020 Sep;89:55-60.e6. doi: 10.1016/j.exphem.2020.08.002. Epub 2020 Aug 8. Exp Hematol. 2020. PMID: 32781097 Free article. Clinical Trial.
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.
Baliakas P, Agathangelidis A, Hadzidimitriou A, Sutton LA, Minga E, Tsanousa A, Scarfò L, Davis Z, Yan XJ, Shanafelt T, Plevova K, Sandberg Y, Vojdeman FJ, Boudjogra M, Tzenou T, Chatzouli M, Chu CC, Veronese S, Gardiner A, Mansouri L, Smedby KE, Pedersen LB, Moreno D, Van Lom K, Giudicelli V, Francova HS, Nguyen-Khac F, Panagiotidis P, Juliusson G, Angelis L, Anagnostopoulos A, Lefranc MP, Facco M, Trentin L, Catherwood M, Montillo M, Geisler CH, Langerak AW, Pospisilova S, Chiorazzi N, Oscier D, Jelinek DF, Darzentas N, Belessi C, Davi F, Ghia P, Rosenquist R, Stamatopoulos K. Baliakas P, et al. Among authors: langerak aw. Blood. 2015 Jan 29;125(5):856-9. doi: 10.1182/blood-2014-09-600874. Epub 2014 Dec 17. Blood. 2015. PMID: 25634617 Free PMC article.
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.
Mansouri L, Sutton LA, Ljungström V, Bondza S, Arngården L, Bhoi S, Larsson J, Cortese D, Kalushkova A, Plevova K, Young E, Gunnarsson R, Falk-Sörqvist E, Lönn P, Muggen AF, Yan XJ, Sander B, Enblad G, Smedby KE, Juliusson G, Belessi C, Rung J, Chiorazzi N, Strefford JC, Langerak AW, Pospisilova S, Davi F, Hellström M, Jernberg-Wiklund H, Ghia P, Söderberg O, Stamatopoulos K, Nilsson M, Rosenquist R. Mansouri L, et al. Among authors: langerak aw. J Exp Med. 2015 Jun 1;212(6):833-43. doi: 10.1084/jem.20142009. Epub 2015 May 18. J Exp Med. 2015. PMID: 25987724 Free PMC article.
Targeting Signaling Pathways in Chronic Lymphocytic Leukemia.
Muggen AF, Singh SP, Hendriks RW, Langerak AW. Muggen AF, et al. Among authors: langerak aw. Curr Cancer Drug Targets. 2016;16(8):669-688. doi: 10.2174/1568009616666160408145623. Curr Cancer Drug Targets. 2016. PMID: 27055580 Review.
Cell lines generated from a chronic lymphocytic leukemia mouse model exhibit constitutive Btk and Akt signaling.
Singh SP, Pillai SY, de Bruijn MJW, Stadhouders R, Corneth OBJ, van den Ham HJ, Muggen A, van IJcken W, Slinger E, Kuil A, Spaargaren M, Kater AP, Langerak AW, Hendriks RW. Singh SP, et al. Among authors: langerak aw. Oncotarget. 2017 May 26;8(42):71981-71995. doi: 10.18632/oncotarget.18234. eCollection 2017 Sep 22. Oncotarget. 2017. PMID: 29069762 Free PMC article.
Rituximab addition to chemotherapy in real world patients with chronic lymphocytic leukemia: effective in first line but indication of lack of efficacy in subsequent lines of therapy.
van der Straten L, Dinmohamed AG, Westerweel PE, Langerak AW, Riedl J, Doorduijn JK, Kater AP, Levin MD. van der Straten L, et al. Among authors: langerak aw. Leuk Lymphoma. 2018 Nov;59(11):2757-2761. doi: 10.1080/10428194.2018.1452215. Epub 2018 Apr 4. Leuk Lymphoma. 2018. PMID: 29616852 No abstract available.
Flow cytometry shows added value in diagnosing lymphoma in brain biopsies.
van der Meulen M, Bromberg JEC, Lam KH, Dammers R, Langerak AW, Doorduijn JK, Kros JM, van den Bent MJ, van der Velden VHJ. van der Meulen M, et al. Among authors: langerak aw. Cytometry B Clin Cytom. 2018 Nov;94(6):928-934. doi: 10.1002/cyto.b.21641. Epub 2018 Sep 3. Cytometry B Clin Cytom. 2018. PMID: 29747221 Free PMC article.
294 results