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Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation.
Leeson-Payne A, Iyinikkel J, Malcolm C, Lam BYH, Sommer N, Dowsett GKC, Martinez de Morentin PB, Thompson D, Mackenzie A, Chianese R, Kentistou K, Gardner EJ, Perry JRB, Grassmann F, Speakman JR, Rochford JJ, Yeo GSH, Murray F, Heisler LK. Leeson-Payne A, et al. Among authors: martinez de morentin pb. Cell Metab. 2024 May 7;36(5):1076-1087.e4. doi: 10.1016/j.cmet.2024.03.016. Epub 2024 Apr 22. Cell Metab. 2024. PMID: 38653246
Editorial: Role of estrogens as key regulators of energy homeostasis.
Novelle MG, Camacho-Morales A, Martínez De Morentin PB. Novelle MG, et al. Among authors: martinez de morentin pb. Front Endocrinol (Lausanne). 2023 Sep 6;14:1279619. doi: 10.3389/fendo.2023.1279619. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37745709 Free PMC article. No abstract available.
Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression.
Wagner S, Brierley DI, Leeson-Payne A, Jiang W, Chianese R, Lam BYH, Dowsett GKC, Cristiano C, Lyons D, Reimann F, Gribble FM, Martinez de Morentin PB, Yeo GSH, Trapp S, Heisler LK. Wagner S, et al. Among authors: martinez de morentin pb. Mol Metab. 2023 Feb;68:101665. doi: 10.1016/j.molmet.2022.101665. Epub 2022 Dec 30. Mol Metab. 2023. PMID: 36592795 Free PMC article.
Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress.
González-García I, Contreras C, Estévez-Salguero Á, Ruíz-Pino F, Colsh B, Pensado I, Liñares-Pose L, Rial-Pensado E, Martínez de Morentin PB, Fernø J, Diéguez C, Nogueiras R, Le Stunff H, Magnan C, Tena-Sempere M, López M. González-García I, et al. Among authors: martinez de morentin pb. Cell Rep. 2018 Oct 9;25(2):413-423.e5. doi: 10.1016/j.celrep.2018.09.038. Cell Rep. 2018. PMID: 30304681 Free PMC article.
Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake.
D'Agostino G, Lyons D, Cristiano C, Lettieri M, Olarte-Sanchez C, Burke LK, Greenwald-Yarnell M, Cansell C, Doslikova B, Georgescu T, Martinez de Morentin PB, Myers MG Jr, Rochford JJ, Heisler LK. D'Agostino G, et al. Among authors: martinez de morentin pb. Cell Metab. 2018 Oct 2;28(4):619-630.e5. doi: 10.1016/j.cmet.2018.07.017. Epub 2018 Aug 23. Cell Metab. 2018. PMID: 30146485 Free PMC article.
mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol.
González-García I, Martínez de Morentin PB, Estévez-Salguero Á, Contreras C, Romero-Picó A, Fernø J, Nogueiras R, Diéguez C, Tena-Sempere M, Tovar S, López M. González-García I, et al. Among authors: martinez de morentin pb. J Endocrinol. 2018 Sep;238(3):177-186. doi: 10.1530/JOE-18-0190. Epub 2018 Jun 18. J Endocrinol. 2018. PMID: 29914932 Free PMC article.
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