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Mediator kinase inhibition reverses castration resistance of advanced prostate cancer.
Li J, Hilimire TA, Yueying L, Wang L, Liang J, Győrffy B, Sikirzhytski V, Ji H, Zhang L, Cheng C, Ding X, Kerr KR, Dowling CE, Chumanevich AA, Mack ZT, Schools GP, Lim CU, Ellis L, Zi X, Porter DC, Broude EV, McInnes C, Wilding G, Lilly MB, Roninson IB, Chen M. Li J, et al. Among authors: roninson ib. J Clin Invest. 2024 Mar 28:e176709. doi: 10.1172/JCI176709. Online ahead of print. J Clin Invest. 2024. PMID: 38546787 Free article.
CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.
Chen M, Li J, Zhang L, Wang L, Cheng C, Ji H, Altilia S, Ding X, Cai G, Altomare D, Shtutman M, Byrum SD, Mackintosh SG, Feoktistov A, Soshnikova N, Mogila VA, Tatarskiy V, Erokhin M, Chetverina D, Prawira A, Ni Y, Urban S, McInnes C, Broude EV, Roninson IB. Chen M, et al. Among authors: roninson ib. Nucleic Acids Res. 2023 Aug 11;51(14):7288-7313. doi: 10.1093/nar/gkad538. Nucleic Acids Res. 2023. PMID: 37378433 Free PMC article.
Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo.
Ding X, Sharko AC, McDermott MSJ, Schools GP, Chumanevich A, Ji H, Li J, Zhang L, Mack ZT, Sikirzhytski V, Shtutman M, Ivers L, O'Donovan N, Crown J, Győrffy B, Chen M, Roninson IB, Broude EV. Ding X, et al. Among authors: roninson ib. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2201073119. doi: 10.1073/pnas.2201073119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914167 Free PMC article.
Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types.
Erokhin M, Chetverina O, Győrffy B, Tatarskiy VV, Mogila V, Shtil AA, Roninson IB, Moreaux J, Georgiev P, Cavalli G, Chetverina D. Erokhin M, et al. Among authors: roninson ib. Cancers (Basel). 2021 Jun 24;13(13):3155. doi: 10.3390/cancers13133155. Cancers (Basel). 2021. PMID: 34202528 Free PMC article.
Genome Editing As an Approach to the Study of in Vivo Transcription Reprogramming.
Silaeva YY, Kalmykov VA, Varlamova EA, Korshunov EN, Korshunova DS, Kubekina MV, Shtil AA, Roninson IB, Deykin AV. Silaeva YY, et al. Among authors: roninson ib. Dokl Biochem Biophys. 2020 Jan;490(1):43-46. doi: 10.1134/S1607672920010147. Epub 2020 Apr 27. Dokl Biochem Biophys. 2020. PMID: 32342312
147 results