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Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study.
Haasnoot KJC, Backes Y, Moons LMG, Kranenburg O, Trinh A, Vermeulen L, Noë M, Tuynman JB, van Lent AUG, van Ginneken R, Seldenrijk CA, Raicu MG, Trumpi K, Ubink I, Milne AN, Boonstra JJ, Groen JN, Schwartz MP, Wolfhagen FHJ, Geesing JMJ, Ter Borg F, Brosens LAA, van Bergeijk J, Spanier BWM, de Vos Tot Nederveen Cappel WH, Kessels K, Seerden TCJ, Vleggaar FP, Offerhaus GJA, Siersema PD, Elias SG, Laclé MM; Dutch T1 CRC Working Group. Haasnoot KJC, et al. Among authors: vermeulen l. Mod Pathol. 2020 Dec;33(12):2626-2636. doi: 10.1038/s41379-020-0598-9. Epub 2020 Jun 24. Mod Pathol. 2020. PMID: 32581367 Free article.
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients.
de Sousa E Melo F, Colak S, Buikhuisen J, Koster J, Cameron K, de Jong JH, Tuynman JB, Prasetyanti PR, Fessler E, van den Bergh SP, Rodermond H, Dekker E, van der Loos CM, Pals ST, van de Vijver MJ, Versteeg R, Richel DJ, Vermeulen L, Medema JP. de Sousa E Melo F, et al. Among authors: vermeulen l. Cell Stem Cell. 2011 Nov 4;9(5):476-85. doi: 10.1016/j.stem.2011.10.008. Cell Stem Cell. 2011. PMID: 22056143 Free article.
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.
De Sousa E Melo F, Wang X, Jansen M, Fessler E, Trinh A, de Rooij LP, de Jong JH, de Boer OJ, van Leersum R, Bijlsma MF, Rodermond H, van der Heijden M, van Noesel CJ, Tuynman JB, Dekker E, Markowetz F, Medema JP, Vermeulen L. De Sousa E Melo F, et al. Among authors: vermeulen l. Nat Med. 2013 May;19(5):614-8. doi: 10.1038/nm.3174. Epub 2013 Apr 14. Nat Med. 2013. PMID: 23584090
Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry.
Trinh A, Trumpi K, De Sousa E Melo F, Wang X, de Jong JH, Fessler E, Kuppen PJ, Reimers MS, Swets M, Koopman M, Nagtegaal ID, Jansen M, Hooijer GK, Offerhaus GJ, Kranenburg O, Punt CJ, Medema JP, Markowetz F, Vermeulen L. Trinh A, et al. Among authors: vermeulen l. Clin Cancer Res. 2017 Jan 15;23(2):387-398. doi: 10.1158/1078-0432.CCR-16-0680. Epub 2016 Jul 26. Clin Cancer Res. 2017. PMID: 27459899
Neoadjuvant chemotherapy affects molecular classification of colorectal tumors.
Trumpi K, Ubink I, Trinh A, Djafarihamedani M, Jongen JM, Govaert KM, Elias SG, van Hooff SR, Medema JP, Lacle MM, Vermeulen L, Borel Rinkes IHM, Kranenburg O. Trumpi K, et al. Among authors: vermeulen l. Oncogenesis. 2017 Jul 10;6(7):e357. doi: 10.1038/oncsis.2017.48. Oncogenesis. 2017. PMID: 28692036 Free PMC article.
Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data.
Trinh A, Lädrach C, Dawson HE, Ten Hoorn S, Kuppen PJK, Reimers MS, Koopman M, Punt CJA, Lugli A, Vermeulen L, Zlobec I. Trinh A, et al. Among authors: vermeulen l. Br J Cancer. 2018 Nov;119(10):1244-1251. doi: 10.1038/s41416-018-0230-7. Epub 2018 Nov 2. Br J Cancer. 2018. PMID: 30385823 Free PMC article.
Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer.
Roseweir AK, Park JH, Hoorn ST, Powell AG, Aherne S, Roxburgh CS, McMillan DC, Horgan PG, Ryan E, Sheahan K, Vermeulen L, Paul J, Harkin A, Graham J, Sansom O, Church DN, Tomlinson I, Saunders M, Iveson TJ, Edwards J. Roseweir AK, et al. Among authors: vermeulen l. J Pathol Clin Res. 2020 Oct;6(4):283-296. doi: 10.1002/cjp2.171. Epub 2020 May 13. J Pathol Clin Res. 2020. PMID: 32401426 Free PMC article.
Interconnectivity between molecular subtypes and tumor stage in colorectal cancer.
Coebergh van den Braak RRJ, Ten Hoorn S, Sieuwerts AM, Tuynman JB, Smid M, Wilting SM, Martens JWM, Punt CJA, Foekens JA, Medema JP, IJzermans JNM, Vermeulen L. Coebergh van den Braak RRJ, et al. Among authors: vermeulen l. BMC Cancer. 2020 Sep 4;20(1):850. doi: 10.1186/s12885-020-07316-z. BMC Cancer. 2020. PMID: 32887573 Free PMC article.
348 results